Night-time economies have traditionally clustered in city centres and nightlife districts. Yet, due to regulation, urban regeneration and gentrification, nightlife activities and spaces, including nightclubs and club nights, are increasingly located across cities. However, the significance and spatial dynamics of this diffusion and the relationships between different nocturnal spaces and scales remain poorly understood. This paper examines the intra-urban dispersal of nightclubs in Amsterdam and the ways in which nightclub promoters attune their curatorial practices to urban processes through genre-based commercial and cultural imperatives. Drawing on interviews with 36 nightclub promoters, 111€‰hours of participant observation at clubs and document-based analysis, it demonstrates how these reflexive actors respond and contribute to intra-urban dispersal by (1) spatialising music genres, (2) staging affective atmospheres at different scales and (3) spatialising audiences. The paper contributes to studies which focus on nocturnal spaces, actors and activities and the evolving urban geography within cities.