The COVID-19 new deaths' highest numbers in Southeast Asia were reported from Indonesia, with 8,784 new deaths. Healthcare workers (HCWs) have several roles in the COVID-19 vaccine implementation. This study aimed to assess COVID-19 vaccine perception and belief among HCWs and identify demographic mapping by using the geographical information system. This study used a quantitative method with cross-sectional design, wherein 112 registered HCWs in the Indonesian hospital and healthcare centre were shared a survey questionnaire using Google Forms® and then visualised it through geographic mapping. The perception of HCWs regarding the COVID-19 vaccine was considered good but in contrast to the belief. There was a significant relationship between age [p value = .021; odds ratio (OR): 2.692; 95% confidence interval (CI): 1.229-5.896] and also HCWs' workplace (p value = .040; OR: 0.231; 95% CI: 0.0620-0.862) towards the belief of HCWs regarding the COVID-19 vaccine. Developing strategies to decrease HCWs and public hesitation and increase trust is vital for implementing vaccination programmes.